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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCF21
All Species:
18.18
Human Site:
S73
Identified Species:
36.36
UniProt:
O43680
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43680
NP_003197.2
179
19715
S73
K
S
P
L
S
G
V
S
Q
E
G
K
Q
V
Q
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
A79
G
K
R
G
K
K
S
A
G
C
G
G
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001100774
179
19679
S73
K
S
P
L
S
G
V
S
Q
E
G
K
Q
V
Q
Dog
Lupus familis
XP_541110
269
28873
S163
K
S
P
L
S
G
V
S
Q
E
G
K
Q
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35437
179
19663
S73
K
S
P
L
S
G
V
S
Q
E
G
K
Q
V
Q
Rat
Rattus norvegicus
P97831
160
18106
E63
P
S
A
Q
S
F
E
E
L
Q
S
Q
R
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507254
177
19432
S72
K
S
P
L
N
G
V
S
Q
E
G
K
Q
V
Q
Chicken
Gallus gallus
P79782
183
20177
A68
K
Q
R
Q
A
A
N
A
R
E
R
D
R
T
Q
Frog
Xenopus laevis
Q6GNB7
179
19771
N73
K
S
P
L
G
T
I
N
Q
E
G
K
Q
V
Q
Zebra Danio
Brachydanio rerio
Q32PV5
176
19327
A70
R
S
A
P
N
G
V
A
Q
E
G
K
Q
V
Q
Tiger Blowfish
Takifugu rubipres
NP_001027853
144
16237
D47
Y
S
D
E
E
L
D
D
D
G
A
E
V
G
R
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10574
142
16461
D45
L
D
S
P
N
Y
P
D
S
L
S
N
G
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
99.4
65.4
N.A.
96
27.9
N.A.
89.9
32.2
86
75.4
44.1
N.A.
N.A.
27.3
N.A.
Protein Similarity:
100
40.7
100
66.1
N.A.
98.3
46.9
N.A.
92.7
53
92.7
86
53.6
N.A.
N.A.
40.2
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
13.3
N.A.
93.3
20
73.3
66.6
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
40
N.A.
100
46.6
86.6
86.6
20
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
9
0
25
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
9
17
9
0
0
9
0
0
0
% D
% Glu:
0
0
0
9
9
0
9
9
0
67
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
9
50
0
0
9
9
67
9
17
25
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% I
% Lys:
59
9
0
0
9
9
0
0
0
0
0
59
0
0
0
% K
% Leu:
9
0
0
50
0
9
0
0
9
9
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
9
9
0
0
0
9
0
0
0
% N
% Pro:
9
0
50
17
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
17
0
0
0
0
59
9
0
9
59
0
67
% Q
% Arg:
9
0
17
0
0
0
0
0
9
0
9
0
17
0
9
% R
% Ser:
0
75
9
0
42
0
9
42
9
0
17
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
50
0
0
0
0
0
9
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _